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Rifampicin CAS#13292-46-1

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  • Rifampicin CAS#13292-46-1
  • Rifampicin CAS#13292-46-1
  • Rifampicin CAS#13292-46-1
  • Rifampicin CAS#13292-46-1
  • Rifampicin CAS#13292-46-1

›

Rifampicin CAS#13292-46-1

Broad-Spectrum Antibacterial Activity: Rifampicin is a broad-spectrum rifamycin antibiotic effective against Mycobacterium tuberculosis, Gram-positive bacteria, Gram-negative bacteria, and certain viruses.


Strong Anti-Tuberculosis Efficacy: It provides a powerful antibacterial effect against tuberculosis bacteria, making it a core agent in anti-TB therapy.


Synergistic Combination Therapy: When used in combination with other anti-tuberculosis drugs, it delivers a synergistic therapeutic effect, improving overall treatment outcomes.


Helps Delay Drug Resistance: Combination use can effectively delay the development of drug-resistant strains, supporting long-term clinical efficacy.



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Product Description

Product Description of Rifampicin CAS#13292-46-1

Rifampicin is a broad-spectrum rifamycin antibiotic. It strongly acts on tubercle bacilli, various gram-positive, gram-negative bacteria and partial viruses.

It is red crystalline powder insoluble in water, mainly made into oral dosage forms. Combined with other anti-tuberculosis drugs, it produces synergistic effects and delays drug resistance, serving as a core drug for tuberculosis therapy.


Product Application of Rifampicin CAS#13292-46-1

Rifampicin is a broad-spectrum, cell-penetrating bactericidal antibiotic active against Mycobacterium tuberculosis, Gram-positive and some Gram-negative bacteria. It is mainly used to treat drug-resistant tuberculosis, drug-resistant Staphylococcus aureus infections and leprosy. It also serves as a pharmaceutical intermediate with the same antibacterial spectrum, showing good efficacy against Gram-positive cocci and Mycobacterium tuberculosis.

Product Information

Parameters


storage temp.2-8°C
solubilitychloroform: soluble50mg/mL, clear
pka1.7, 7.9(at 25℃)
formcrystalline
colorfaint red to very dark red
Water SolubilitySoluble in DMSO or methanolSoluble in water, ethyl acetate, chloroform, methanol, tetrahydrofuran and dimethyl sulfoxide.
Merck148216
BRN5723476
Specific ActivityAntibacterial
BCS Class2
Stability:Hygroscopic, Light Sensitive
IARC3 (Vol. 24, Sup 7) 1987
EPA Substance Registry SystemRifampin (13292-46-1)


Safety Information


Hazard CodesXn,Xi
Risk Statements22-36/37/38-36/38
Safety Statements26-36-37/39
WGK Germany3
RTECSVJ7000000
F39742
HS Code29419000
Hazardous Substances Data13292-46-1(Hazardous Substances Data)
ToxicityLD50 in mice, rats (mg/kg): 885, 1720 orally; 260, 330 i.v.; 640, 550 i.p. (Fürész)


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