1,3-Dimercaptopropane Product Description CAS#109-80-8

1,3-Dimercaptopropane (1,3-Propanedithiol) is an organosulfur compound with the molecular formula C₃H₈S₂ and a molecular weight of 108.22. It is a colorless to pale yellow transparent liquid at room temperature and pressure, with a strong thiol-like odor. Its melting point is –79°C, boiling point is 169°C, density is 1.078 g/mL (20°C), flash point is 63°C, and refractive index is 1.539. It is slightly soluble in water and miscible with most organic solvents such as ethanol, ether, chloroform, and benzene. Industrially, 1,3-Dimercaptopropane is mainly prepared by reacting 1,3-dihalopropane with hydrogen sulfide or sodium hydrosulfide. This compound contains two highly reactive thiol (–SH) functional groups, giving it strong reducing properties and abundant reactivity. 1,3-Dimercaptopropane can participate in a variety of chemical reactions, including condensation with aldehydes and ketones to form thioacetals or thioketals, substitution reactions with haloalkanes, and oxidation to form disulfides. These unique chemical properties make it valuable for applications in organic synthesis, materials science, and coordination chemistry.

1,3-Dimercaptopropane Applications CAS#109-80-8

1,3-Dimercaptopropane is an important organic synthesis reagent and multifunctional intermediate, widely used in various chemical fields. In organic synthesis, it is mainly used for the reversible protection of aldehydes and ketones. Through reaction with carbonyl compounds, it generates 1,3-dithiane derivatives, which are an important source of carbonyl protecting groups. This dithiane intermediate can also be used for umpolung reactions, expanding the design space of synthetic routes. In materials science, 1,3-dimercaptopropane serves as a bifunctional crosslinking agent and building block in the synthesis and modification of polymers. Crosslinking via enylthiol click reactions can prepare crosslinked anion exchange membranes with high oxidative stability and high ionic conductivity. In coordination chemistry, it can act as a bidentate ligand to form stable complexes with various metal ions. In the electroplating industry, 1,3-dimercaptopropane can be used as an additive in CoNi alloy electroplating solutions to effectively inhibit abnormal deposition and obtain coatings with fine grains, smooth surfaces, and low internal stress. In the fragrance industry, after appropriate chemical modification, it can be used as an intermediate in the synthesis of special aroma fragrances. Furthermore, 1,3-dimercaptopropane can also be used in the design and preparation of fluorescent probes, and in the formulation of cleaning agents for laboratory glassware.